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Biomarkers of mitochondrial dynamics in idiopathic pulmonary fibrosis: Identification and validation through transcriptomic and single-cell analyses

Fig 2

Identification of CD247, RETN, and IL7R as biomarkers using a comprehensive analysis of 101 machine-learning models.

(A) AUC values of the models on the training and validation sets. (B) and (C) ROC curves of the optimal model in the training and validation sets, respectively. (D) and (E) Boxplots of feature gene expression levels in the training and validation sets, respectively. Red represents IPF samples, and blue represents control samples. (F) and (G) ROC curves of feature genes in the training and validation sets, respectively.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0347845.g002