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Node properties of biomarkers within the protein–protein interaction network derived from breast cancer-associated genes

Fig 5

Spearman’s rank correlation coefficient and hierarchical clustering of centrality rankings for BC biomarkers.

The analysis used 62 biomarkers with a degree of ≥1 from the PPI network based on 1,500 query genes. Two biomarkers with a degree of 0 (HOXB13 and SLC39A) were excluded. BC: Breast Cancer, PPI: protein–protein interaction.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0347551.g005