Deciphering the molecular network of Trichostatin A in regulating Alzheimer’s disease screening of core genes and mechanistic investigation based on multidimensional bioinformatics and molecular simulation
Fig 6
Immune infiltration characteristics of AD and correlation with 8 core genes analyzed via CIBERSORT.
(A). Immune cell abundance heatmap of the training set (142 Ctrl, 153 AD cases). (B). Spearman correlation heatmap of infiltrating immune cell populations. (C). Box plot of differentially infiltrated immune cells between AD and Ctrl groups (* P < 0.05, *** P < 0.001). (D). Spearman correlation heatmap between core genes and infiltrating immune cells, significant results (adjusted P < 0.05) marked in bold.