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Evaluation of AT121 versus morphine on cortical neurons electrophysiology and dopamine concentrations in hippocampal cells

Fig 14

Effects of morphine and AT121 on dopamine concentration in hippocampal cell culture.

Mean ± SD dopamine concentrations are illustrated after 30 minutes of treatment in culture dishes, measured using sandwich ELISA analysis at 450 nm. Statistical significance (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001) (Tukey’s multiple comparisons Test) (n = 4 × 3 culture dishes).

Fig 14

doi: https://doi.org/10.1371/journal.pone.0347529.g014