Evaluation of AT121 versus morphine on cortical neurons electrophysiology and dopamine concentrations in hippocampal cells
Fig 8
Modulation of cells membrane current in pyramidal cells by morphine, AT121, acetylcholine, and naloxone.
Mean ± SD amplitude is shown for 8 pyramidal cells isolated from newborn mouse cerebral cortex, after 5-minutes of exposure to each compound (10 μg/ml) in culture medium (n = 7 × 8 cells). (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).