Evaluation of AT121 versus morphine on cortical neurons electrophysiology and dopamine concentrations in hippocampal cells
Fig 5
Effects of morphine, AT121, acetylcholine, and naloxone on stimulation threshold in pyramidal cells from newborn mice.
The chart illustrates the mean ± standard deviation of the stimulation threshold in pyramidal cells isolated from the cerebral cortex of newborn mice, after 5-minutes of exposure to each of the specified compounds (10 μg/ml) in the culture medium (n = 7 × 8 cells) (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).