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Evaluation of AT121 versus morphine on cortical neurons electrophysiology and dopamine concentrations in hippocampal cells

Fig 3

Modulation of action potential phases in newborn mice cerebral cortex pyramidal cells by morphine, AT121, acetylcholine, and naloxone.

Mean total time ± SD is shown for each compound (10 µg/ml) added to the culture medium for 5 minutes. Statistical significance: (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001), (n = 7 × 8 cells).

Fig 3

doi: https://doi.org/10.1371/journal.pone.0347529.g003