Beyond individual markers: Prognostic value of the combined CEA/PNI score in metastatic colorectal cancer as a predictor of survival
Fig 3
Progression-free survival according to the combined CEA/PNI score at baseline.
Kaplan–Meier survival curves for progression-free survival (PFS) stratified by the combined carcinoembryonic antigen (CEA) and prognostic nutritional index (PNI) score at baseline. Patients were classified into four groups: CEAHIGH & PNILOW, CEAHIGH & PNIHIGH, CEALOW & PNILOW, and CEALOW & PNIHIGH. The high-risk group (CEAHIGH & PNILOW) showed significantly worse PFS compared to the reference group (CEALOW & PNIHIGH), with a hazard ratio (HR) of 2.16 (95% confidence interval [CI]: 1.24–3.75; p < 0.001). Survival distributions were compared using the log-rank test.