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Day–night variation and age-related differences in gadolinium-based contrast media enhancement in the brain: A T1 mapping study

Fig 3

Scatterplots of ΔT1 versus age in the cerebral cortex.

Scatterplots depict the relationship between age (x-axis) and change in T1 relaxation time (ΔT1, y-axis) across four distinct cortical regions. In each plot, data points and their corresponding linear regression lines are stratified by scan time: daytime (blue) and nighttime (gray). Across all regions, a consistent negative correlation indicates that GBCA enhancement becomes more pronounced with increasing age, a trend irrespective of scan time.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0346730.g003