Single-cell profiling unveils key regulators of skeletal stem cells in chicken and human embryonic limb development
Fig 2
Cluster analysis of cell types of human embryonic limb buds and embryonic chicken hindlimbs.
A. Integration analysis of human embryonic limb bud (5 WPC) and chicken hindlimb (HH25). B. Integration analysis of human embryonic long bone (8 WPC) and chicken hindlimb (HH25). C. Integration analysis of human embryonic limb bud (5 WPC) and chicken hindlimb (HH29). D. Integration analysis of human embryonic long bone (8 WPC) and chicken hindlimb (HH29). E. Integration analysis of human embryonic limb bud (5 WPC) and chicken hindlimb (HH31). F. Integration analysis of human embryonic long bone. The degree of overlap reflects transcriptional similarity after CCA-based integration and should not be interpreted as a precise temporal alignment between human and chicken developmental stages. All figures were generated by the authors using original data in R.