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Machine learning-based unified models for predicting drug clearance from pharmacokinetic animal and study design variables

Fig 2

3D scatter plot representing the dataset (raw/imbalanced) used to develop the clearance/clearance/F(bioavailability) prediction model.

This plot contains a representative dataset used in the model development (A) clearance data distribution corresponding to drug and route of administration, (B) clearance data distribution corresponding to drug and animal.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0346432.g002