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Bioinformatics analysis and qRT-PCR validation of iron metabolism-related genes in pediatric asthma

Fig 13

qRT-PCR validation of biomarkers in clinical samples.

(A-D) Relative mRNA expression levels of C19orf12, GDF15, XK and IREB2 were measured in peripheral blood samples obtained from patients with PA (n = 12) and Controls (n = 8). Data are presented as mean ± standard error of mean of relative quantification values calculated using the 2^ − ΔΔCt method with β-actin as the internal reference. Statistical significance was assessed by unpaired Student’s t-test. *p < 0.05, **p < 0.01, ***p < 0.001.

Fig 13

doi: https://doi.org/10.1371/journal.pone.0346063.g013