Multiple omics analyses and experiments validation identify PRDX3 as a biomarker of prognosis and antioncogene in kidney clear cell carcinoma
Fig 9
PRDX3 over-expression inhibited tumor progression in KIRC cells.
A: Western blot showing PRDX3 over-expression in 786−0 and Caki-1 cells. B: qPCR showing elevated PRDX3 in KIRC cells. Data (n = 3) are shown as mean ± standard error (SE), * = P < 0.05; ** = P < 0.01; *** = P < 0.001; **** = P < 0.0001. C: PRDX3 over-expression inhibited wound healing. Data are shown as mean ± standard error (SE), * = P < 0.05; ** = P < 0.01; *** = P < 0.001; **** = P < 0.0001. D and E: PRDX3 over-expression inhibited migration and invasion in KIRC cells. Data are shown as mean ± standard error (SE), * = P < 0.05; ** = P < 0.01; *** = P < 0.001; **** = P < 0.0001.