Maternal undernutrition reprograms reproductive and metabolic phenotypes in female offspring of the rabbit model
Fig 5
Relative mRNA abundance of target genes in (a) oocytes, (b) cumulus cells (CCs), and (c) blastocysts from female offspring (F1).
Samples were obtained from 16-week-old female offspring (F1) of dams subjected to moderate food restriction during the first two-thirds of gestation (FR group) or fed ad libitum throughout pregnancy (C group). Group C: n = 41 oocytes with their corresponding CCs, and 32 blastocysts; Group FR: n = 56 oocytes with their corresponding CCs, and 40 blastocysts. Data are presented as the mean ± SEM. Bars with different superscripts indicate significant differences between C and FR groups for each gen [a, b (P < 0.05)] or a trend [(*) P = 0.07].