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Stirred tank bioreactor process for chikungunya vaccine candidate VEEV-ΔC-CHIKV

Fig 2

Comparison of VEEV-ΔC-CHIKV cultivation processes using microcarriers and Fibra-Cel carriers bioreactors.

(A) Glucose consumption. (B) Glutamine consumption. (C) Lactate concentration in the bioreactor. (D) Glucose concentration in the bioreactor. (E) Glutamine concentration in the bioreacor. (F) Glutamate concentration in the bioreactor. (G) Oxygen consumption. (H) Virus titer under both carriers. (I) Total virus concentration obtained under both carriers. Glucose, Glc; Glutamine, Gln; Glutamate, Glu; Lactate, Lac.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0344564.g002