Integrating sequence-based GWAS and comparative genomic analysis reveals conservation and species-specificity of putative functional variants influencing tail length and tail abnormalities in pigs and sheep
Fig 2
Conserved and species-specific elements in GWAS loci for tail length in sheep and pigs.
Manhattan plots labeled with conserved and species-specific elements identified within genomic windows of GWAS loci for tail length in sheep (A) and pigs (B). The genomic window of the suggestive locus on OAR4:107,294,668 in sheep and the significant locus on SSC18:7,836,326 in pigs are conserved, harboring 6 putatively functional common genes. Eight species-specific putative functional candidate genes were identified on OAR11, OAR21, and OAR23 in sheep, and 5 species-specific putative functional candidate genes on SSC1, SSC10, and SSC16 in pigs.