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Comprehensive analysis of the potential effect and mechanism of pyroptosis-related genes in treatment-related myeloid tumors

Fig 5

PPI network and hub gene analysis.

A–B. PPI network of PRDEGs. STRING interaction network diagram (A), Cytoscape interaction network diagram (B). C–G. PPI network calculated by five algorithms of the cytoHubba plugin: MCC (C), MNC (D), degree (E), EPC (F), and closeness (G). H. Venn diagram shows the intersection of the top 10 PRDEGs from the five algorithms of the cytoHubba plugin. PRDEGs, pyroptosis related differentially expressed genes; t-MN, therapy-related myeloid neoplasm; PPI, protein–protein interaction.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0343525.g005