Gastrin ameliorates heart failure and suppresses myocardial remodeling via the JAK2/STAT3 and ERK1/2 pathways
Fig 3
The impact of gastrin on ISO-induced myocardial fibrosis in vivo(1).
(A)Masson trichrome staining images of each group(200x magnification); (B)Immunohistochemical staining images for collagen I and collagen III of each group(200x magnification); (C)The relative fibrotic area as demonstrated by Masson's trichrome staining; (D) Quantitative analysis of type I collagen areas; (E)Quantitative analysis of type III collagen areas.*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. The data are presented as the mean±SEM. One-way ANOVA with Tukey’s post-hoc was conducted for (Panel C-E).