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Global, regional, and national burden of nonalcoholic fatty liver disease among adults aged ≥ 45 years: A comprehensive analysis of epidemiological trends and projections to 2035

Fig 3

Sex-Stratified Trends in Age-Standardized DALY Rates (1990–2021) A: Both sexes.

Eastern Europe showed the steepest increase (EAPC = 3.36). B: Females. Andean Latin America had the highest rates with rising trajectories. C: Males. Southern Sub-Saharan Africa experienced sharp increases before stabilizing post-1998. Abbreviations: EAPC, Estimated Annual Percentage Change. Shaded areas represent 95% uncertainty intervals.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0342697.g003