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Global, regional, and national burden of nonalcoholic fatty liver disease among adults aged ≥ 45 years: A comprehensive analysis of epidemiological trends and projections to 2035

Fig 2

Trends in Age-Standardized NAFLD Rates by SDI Quintiles and GBD Regions (1990–2021) A: Incidence rates showing a bell-shaped SDI correlation, peaking in medium-SDI regions (e.g., North Africa/Middle East).

B: Prevalence rates mirroring incidence trends, with highest burdens in medium-SDI regions. C: Mortality rates exhibiting nonlinear SDI associations, highest in Andean and Central Latin America. D: DALY rates highlighting severe burdens in Andean Latin America and Central Latin America. Abbreviations: SDI, Socio-demographic Index; GBD, Global Burden of Disease; ASIR, Age-Standardized Incidence Rate; ASPR, Age-Standardized Prevalence Rate; ASMR, Age-Standardized Mortality Rate; ASDR, Age-Standardized DALY Rate.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0342697.g002