Effects of pentosan polysulfate sodium on joint structure and function out to six months in naturally-occurring canine osteoarthritis
Fig 2
Effect of PPS treatment on index stifle osteoarthritic gait and symmetry.
Total pressure index (TPI%) and symmetry index (SI) analysis. PPS is represented by filled circles and placebo by open triangles. (A) Index hindlimb TPI% for PPS and placebo groups. (B) Percentage change from baseline (%CfB) analysis of TPI%. A 5% or greater increase in the %CfB value was considered to be a clinically meaningful improvement. (C) Ipsilateral SI values from week 1 to week 26. (D) Contralateral SI values from week 1 to 26. Data are represented as mean ± 95% CI. The n for each group and timepoint corresponds to valid gait assessments.