Development of niosomal nanoparticles loaded with cisplatin and vorinostat combination for cancer therapy
Fig 5
FTIR spectral analysis of cisplatin (CIS), vorinostat (VOR), and their formulations.
(A) FTIR spectra of pure CIS, pure VOR, and physical mixture (CIS–VOR), showing characteristic functional group peaks including NH₂ bending, OH stretching, and C = O vibrations. (B) FTIR spectra of CIS–VOR, plain niosomes (NIO), and drug-loaded niosomes (NIO–CIS–VOR), demonstrating characteristic peak shifts and changes in intensity, confirming successful encapsulation of CIS and VOR within the niosomal carrier system.