IGM: Integrated Gene-expression Modeling for multi-condition flux-preserving genome-scale metabolic models
Fig 5
Relative gene expression values and gene expression variable values of Data-A.
(A) Heatmap showing 30 randomly selected relative gene expression profiles (left panel) and gene expression variable values in IGM programming (right panel) across eight conditions: reference (RF), WT0.2 (wild type at 0.2 per hour), WT0.5 (wild type at 0.5 per hour), WT0.7 (wild type at 0.7 per hour), and single gene deletions (pgm, pgi, gapC, zwf, and rpe). The heatmap values range from 0 to 1, with blue indicating values near 0 and yellow indicating values near 1. (B) Histogram showing the distribution of correlation coefficients between relative gene expression values and gene expression variable values. (C) Box plot of correlation coefficients between relative gene expression values and gene expression variable values.