Antibiofilm and antibacterial activity of maslinic acid against Vancomycin-Resistant Enterococci (VRE)
Fig 5
In vivo efficacy of maslinic acid in a Caenorhabditis elegans model of bacterial infection.
C. elegans were infected with VRE, E. faecium NR-31909. After infection, worms were treated with maslinic acid or linezolid at 10 × MIC. After 24 hours, worms were lysed, and bacteria were plated and CFU were counted after 24 hr. Results are expressed as means from three biological replicates ± standard deviation. Statistical analyses were determined by one-way ANOVA with post hoc testing (***p < 0.005), (****p < 0.0001).