Dynamic metabolic modeling of Streptomyces clavuligerus in complex medium highlights nutrient-dependent metabolic transitions associated with clavulanic acid biosynthesis
Fig 5
Topological analysis of the amino acid metabolic network derived from the iLT1021 GEM.
(A) Central hub metabolites and their interaction map, (B) Correlation heatmap of network topology parameters, (C) Quantitative distribution of connectivity metrics across amino acids.