Molecular interplay of ASNS and the PI3K-AKT-mTOR pathway in CMV and HIV co-infections: Therapeutic implications
Fig 2
ASNS expression and enrichment in CMV/HIV infections.
(A) CMV infection upregulates ASNS. (B) HIV-1 infection upregulates ASNS. (C) 42 genes overlap in CMV/HIV. (D) PPI network shows ASNS as top hub. (E) MCC ranks ASNS first. (F) Centrality analysis highlights ASNS. (G) Random Forest confirms ASNS influence. (H) ASNS has high Gini scores. (I) ASNS linked to biosynthesis in CMV. (J) GSEA shows ASNS enrichment in CMV. (K) ASNS associated with biosynthesis in HIV. (L) ASNS role in co-infections underscored.