Childhood cancer burden and health inequality: A systematic analysis from the global burden of diseases study 2021
Fig 3
Relationship Between Age-standardized DALYs Rates and Average Annual Percent Change for Childhood Cancers Across SDI Categories and GBD Regions, Both Sexes Combined, 2021.
This scatter plot illustrates the correlation between ASDR and AAPC for childhood cancers in 2021, across 21 GBD regions and five SDI levels. The vertical dashed red lines represent the 1/3 (−2.02%) and 2/3 (−1.43%) quantiles of AAPC, while the horizontal dashed red lines indicate the 1/3 (270.37 per 100,000) and 2/3 (350.77 per 100,000) quantiles of ASDR. Each point represents a region or SDI level, with color-coded categories reflecting nine combinations of ASDR and AAPC classifications: Low_Low, Low_Medium, Low_High, Medium_Low, Medium_Medium, Medium_High, High_Low, High_Medium, and High_High. Regions in the top-right quadrant (e.g., High_High) exhibit high age-standardized DALYs rates (ASDR) and high average annual percent change (AAPC), indicating both a high burden of childhood cancers and an increasing trend in the DALYs over time. Conversely, regions in the bottom-left quadrant (e.g., Low_Low) show low ASDR and low AAPC, reflecting a lower burden of childhood cancers and slower changes in DALYs over time. DALYs = disability-adjusted life years; AAPC = average annual percent change; ASDR = age-standardized DALYs rate; SDI = Sociodemographic Index; GBD = Global Burden of Disease, Injuries, and Risk Factors Study.