Tissue-specific mitochondrial pathway remodeling linked to longevity in honeybee queens
Fig 6
Control of OXPHOS by the phosphorylation pathway in worker and queen bees across different ages and body regions.
Respiration with combined NSGp-pathways active, prior to decoupling with DNP, illustrating the limitation of OXPHOS by the phosphorylation pathway (1 indicates no limitation and 0 indicates 100% limitation), for the head tissue (A), thoracic muscle (B) and abdominal fat tissue (C). Box plots display the minimum, 25th percentile, median, 75th percentile, and maximum values. Data represent workers at 1 week (early-life, n = 8) and 4 weeks (late-life, n = 12) and queen at 1 week (early-life, n = 4) and 109 weeks (late-life, n = 4). Two-way ANOVA p-values for the effects of bee caste (workers vs. queens), age, and their interaction are indicated in each panel. Panel B did not meet the assumptions; therefore, Kruskal-Wallis test with Dunn’s test was performed instead. Significant differences between ages within a bee caste (shown below the boxes) and between bee castes at the same age (shown above the boxes) are denoted * (P ≤ 0.05), ** (P ≤ 0.01), and *** (P ≤ 0.001).