Integrative genomic analysis reveals DHX58 as a key player in gastric cancer
Fig 5
Screening of key genes and related analysis.
(A) Venn diagram of hypomethylated and highly expressed genes. (B) KEGG circle diagram analysis of key pathways and core genes related to hub genes. (C) mRNA expression level of DHX58 in GC and adjacent tissues from the TCGA database. (D) Spearman correlation analysis of DHX58 and inflammatory pathways. GC, GC-adjacent tissue; TCGA, TCGA. (E) Corresponding gene mutation profiles of the two groups with high and low DHX58 expression levels. DHX58, DExH-box helicase 58; TCGA, The Cancer Genome Atlas.