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Gut microbiome compositional clusters in association with cardiovascular risk: An observational cohort study

Fig 2

Incidence of Major Adverse Cardiac Events During Study Follow-Up.

A. Incidence of Major Adverse Cardiac Events (MACE) in gut microbiome clusters: Cluster H exhibited a significantly higher incidence of cardiac events, mortality, and overall MACE compared to Cluster L (all P < 0.05). Although Cluster H had a higher rate of heart failure compared to Cluster L, the difference did not reach statistical significance (P = 0.076). B. Kaplan-Meier curve depicting MACE-free survival in each cluster during follow-up: MACE-free survival was higher in Cluster L compared to Cluster H (P < 0.001). MACE: Major Adverse Cardiovascular Events.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0341111.g002