Characterization of a spontaneous microphthalmia-like mutant mouse with isolated ocular defects
Fig 6
Electroretinography (ERG) recording analysis of the mutant group and control group.
(A) A thorough evaluation of visual function using ERG was conducted in mice. Representative ERG waveforms from the mutant group (n = 8) and the control group (n = 8) are presented at P4M. (B) Quantitative analysis of a-wave and b-wave amplitudes was performed under dark-adapted conditions at flash intensities of 1.5 cd·s/m² and 3.0 cd·s/m², respectively. **** p < 0.0001 (C) Representative morphology of the eyes in the mutant group and the control group. Pupil atresia was noted in the mutant mice.