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Characterization of a spontaneous microphthalmia-like mutant mouse with isolated ocular defects

Fig 2

The size of the eyeballs and lenses of the mutant group and the control group.

(A) Six eyeballs and six lenses of the mutant group and control group at designated postnatal timepoints (P28, P42, P56, P3M, P4M) are presented on quadrille paper. (B) The size of the eyeballs and lenses were quantified and multiple t tests were used for statistical analysis. The eyeballs and lens of the mutant group(n = 6) are significantly smaller than those of the control group (n = 6). **** p < 0.0001.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0340185.g002