Markers of clinical and mitochondrial adaptation in response to moderate intensity continuous training: A systematic review and meta-analysis
Fig 2
Forest plots of meta-analyses for markers relating to mitochondrial biogenesis.
Effect of moderate intensity continuous training on: (A) Mitochondrial Volume Density, (B) Citrate Synthase Activity, (C) VO2 max, D) Protein Content of MFN2, E) PGC-1α, (F) TFAM (G) DRP1. Positive values favor an increase at post-training, and negative values favor decrease/no change at post-training. Effect sizes are expressed as standardized mean differences (SMD) with 95% confidence internals. Heterogeneity was assessed using the I2 statistic. a* young cohort, b* older cohort.