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Variant calling in genomics: A comparative performance analysis and decision guide

Fig 2

Performance metrics for variant callers on chromosome 20.

Comparison of precision, recall, and F1-score across seven variant calling tools evaluated on the NA12878 chromosome 20 subset. All metrics were calculated using RTG Tools’ vcfeval against the Genome in a Bottle consortium gold standard reference.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0339891.g002