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A novel methodology to characterize beat-to-beat alternations in whole-cell calcium currents

Fig 5

Flowchart of the computational framework for characterizing experimental patch-clamp signals under pulsed clamp voltage.

The diagram starts by loading the data from the path definition, where the patch clamp event log files are stored. Then the current and voltage time series are extracted and properly pre-processed (filtering and interpolation). Then the current signal features are extracted. Finally, the data can be visualised, stored, or a basic statistic of the computed features can be computed.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0339890.g005