An Fc-silent OspA monoclonal antibody passively protects mice from tick and intradermal Borrelia burgdorferi challenge
Fig 5
Cytometric bead array analysis of injection site skin biopsies of BALB/c mice treated with LA-2 and ID infected with B. burgdorferi s.s.
B31. On study day –1, mice were SC administered 30 µg/mL of LA-2 or were left untreated. Mice were ID injected with either B. burgdorferi s.s. B31 or PBS on day 0 and the injection site skin was harvested on day 5 for CBA analysis. Skin samples were diluted 1:2 in assay diluent for analysis. Statistics performed by one-way ANOVA, no matching or pairing, corrected for multiple comparisons using Tukey’s test. 95% confidence interval. *p < 0.05, **p < 0.01.