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Nicotinamide mononucleotide improves spermatogenesis in aluminium-exposed mice by inhibiting NLRP3-mediated pyroptosis

Fig 5

Effect of NMN intervention on NLRP3 and inflammation related genes in testis of mice exposed to aluminum.

A) Effect of NMN intervention on the expression of NLRP3,GSDMD, caspase-1 and IL-1β mRAN in the testis of aluminium-exposed mice; B) Western Blotting detected the effects of NMN intervention on the expression of NLRP3 and inflammation-related gene proteins in the testis of mice exposed to aluminum; C)Image J Analysis of the effects of NMN intervention on the expression of NLRP3,GSDMD, caspase-1 and IL-1β proteins in the testis of aluminium-exposed mice; D) Immunohistochemical detection of NMN intervention on the expression of NLRP3 and inflammation-related gene proteins in testis of aluminum-exposed mice.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0339020.g005