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Anatomical mapping and quantitative functional analysis of lower limb lymphatic flow in normal cynomolgus monkeys using indocyanine green lymphography

Fig 5

Paired comparison of lymphatic contractility metrics between medial and lateral pathways.

Peak–valley analysis demonstrated significantly higher peak frequency and amplitude in the medial pathway compared with that of the lateral pathway, with no difference in mean intensity. Wavelet-based analysis further revealed higher mean frequency and amplitude in the medial pathway, whereas instantaneous frequency standard deviation did not differ significantly. These regional differences were consistently observed across individual limbs, as visualized in the paired line plots. Each line represents paired data from the same limb. *q < 0.05, **q < 0.01 (Wilcoxon signed-rank test with Benjamini–Hochberg correction).

Fig 5

doi: https://doi.org/10.1371/journal.pone.0338516.g005