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Is low birth weight associated with lower adiponectin levels? - A systematic review and meta-analysis

Fig 5

Analysis of pooled Pearson correlations from 19 studies examining the relationship between adiponectin levels and birth weight.

Forest plot showing the correlation between circulating adiponectin levels and birth weight across 19 studies. The pooled estimate is r = 0.31. Heterogeneity is estimated at I2 = 89% (P < 0.0001), assessed using Cochran’s Q and I2 statistics. Pearson correlations (r) were extracted from eligible studies, and 95% CIs were calculated using the random effects model.

SMD, standardized mean difference; CI, confidence interval; I2, heterogeneity.

Twenty data points are presented for 19 studies, as Meral et al. [38] provide a correlation coefficient for both small and large for gestational age.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0335598.g005