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Identification of potential biomarkers and therapeutic targets for underactive bladder based on bioinformatics analysis and experimental validation

Fig 3

Functional enrichment analysis of DEGs, protein-protein interaction (PPI) network construction.

(A) Gene Ontology (GO) analysis of DEGs, including the major biological processes (BP) and molecular functions (MF) involved. (B) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of DEGs. (C) The circular network diagram of functional enrichment analysis. (D) The PPI network constructed from DEGs, with 9 genes in the inner circle having a degree ≥ 15. The color intensity of the genes corresponds to their degree values. (E) Bar chart of the interaction number of each DEG.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0335455.g003