Molecular basis for the activation of the bitter taste receptor TAS2R14 by Ritonavir
Fig 5
Dose-response relationships for hTAS2R14 mutants affect ritonavir activity.
The Results were obtained using a cell-based assay of HEK293E cells co-transfected with hTAS2R14 or its mutants along with Gα16gust44 and GCaMP6s. Mock, without hTAS2R14 receptor transfected cells as a negative control. Each point represents the mean ± SEM from three independent measurements. The figures were plotted by Prism 10. ΔF/F (%), percentage of relative fluorescence increase.