Exposure to the organochlorine pesticide cis-chlordane induces ALS-like mitochondrial perturbations in stem cell-derived motor neurons
Fig 5
cis-Chlordane is detrimental to motor neuron health.
cis-Chlordane treatment causes motor neurons to reduce their oxygen consumption rate, decreases mitochondrial membrane potential (ΔΨm), and increases lysogenic vesicles and ROS in the cell [41].