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Investigating the anti-osteosarcoma effects of Patchouli alcohol through protein network mapping and in vitro experiments

Fig 7

PA inhibits PI3K/AKT pathways in osteosarcoma cells.

Following treatment of 143B and HOS cells with PA (00, 25, 50, and 100 μM) for 24h, protein levels of p-PI3K, PI3K, p-Akt, and Akt as measured by western blot analysis. *p < 0.05 vs. control group.

Fig 7

doi: https://doi.org/10.1371/journal.pone.0332202.g007