Investigating the anti-osteosarcoma effects of Patchouli alcohol through protein network mapping and in vitro experiments
Fig 6
PA triggers autophagy in osteosarcoma cells.
(A) PA-triggered autophagy-related protein LC3I/II and p62 protein expression was detected by Western blot analysis. (B) PA promoted an increased quantities of autophagosomes within 143B and HOS cells as observed by transmission electron microscopy. Red triangles point to autophagosome position. Low magnification, 8000X; High magnification, 30,000X. *p < 0.05 vs. control group.