Cost-effectiveness of primary HPV genotyping and dual-stain or cytology reflex testing versus cytology-based screening for cervical cancer in Chile
Fig 2
Screening algorithms for the PAP-3, hrHPV-CINtec, and hrHPV-PAP comparators.
In the hrHPV–PAP-5 strategy, colposcopy is recommended for patients testing positive for HPV 16/18, or for 12 other+ when the reflex cytology result is ASC-US or higher. If the reflex cytology is NILM, shortened surveillance is advised. A negative test for high-risk HPV returns women to routine screening, with the next HPV DNA test scheduled in 5 years.