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Predicting chromatin conformation contact maps

Fig 2

The Sphinx model.

Each dimension of the 4D input is encoded using latent factors, and the concatenated factors are processed by a multi-layer perceptron. The figure shows an example of predicting the contact between positions 2 and 5 in DNA SPRITE H1-hESC. The final output of the model is the predicted normalized contact count.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0331124.g002