Cohort profile: The Belgian I AM frontier prospective cohort study for comprehensive health outcome exploration
Fig 5
PCA plots of the various longitudinal omics datatypes.
The three principal components (PC) that capture most of the variance in each data type are plotted, resulting in three possible combinations to plot these PC’s on a one-to-one basis. A) clinome data, B) proteomics, C) metabolomics, annotated with gender (M = Male, F = Female) and BMI information. Each point in the plot represents an individual at one specific time point, different measurements from a same individual are represented in one colour. The longitudinal character of the I AM Frontier data reveals that clinical parameters behave more stable over time and produce more dense inter-personal clusters compared to proteomics and metabolomics data. All 30 individuals are rep-resented by a distinct colour. O = BMI < 25, △ = 25 > BMI < 30, 2 = BMI > 30.