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Comparative analysis of extracellular vesicles from induced and adipose-derived Mesenchymal Stem Cells: Implications for regenerative medicine

Fig 5

The effect of iMSC-EVs and ADMSC-EVs on wound healing.

(A) Representative ADMSC images showing the scratched area at different time points 0, 24, and 48 hours (Evos, 4X magnification). Scale bar: 200 μm. (B) The quantification of scratched area μm2 in ADMSC cultures. (* p < 0.05, **** p-value <0.0001, ns-not significant). (C) Representative HDFs images showing the scratched area at 0, 24 and 48 hours (Evos, 4 X magnification) Scale bar: 200 μm. (D) The quantification of the scratched area in HDF cultures as a percentage.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0325065.g005