The lncRNA SENCR knockdown alleviates vascular calcification via miR-4731-5p by suppressing endoplasmic reticulum stress
Fig 5
SENRC promoted the ERS-mediated calcification by suppressing miR-4731-5p expression in VSMCs.
A. Effect of SENRC knockdown or overexpression on miR-4731-5p expression (n = 3); B. miR-4731-5p expression level by RT-qPCR after treatment with miR-4731-5p inhibitor or mimic (n = 3). C and D. Representative bands of Western blotting of cellular ERS-related and phenotypic transformation-related proteins in VSMCs after treatment with miR-4731-5p inhibitor or mimic (n = 3). One-way analysis of variance and Tukey’s post hoc test were used to compare multiple groups. *P < 0.05, **P < 0.01, NS: no significance.