The lncRNA SENCR knockdown alleviates vascular calcification via miR-4731-5p by suppressing endoplasmic reticulum stress
Fig 2
Phenotypic switching and endoplasmic reticulum stress in VSMCs.
A, B, C, D. mRNA levels of SM22-α, Msx-2, Runx2, and ColI in VSMCs (n = 3). E. Representative bands of Western blotting of Runx2, α-SMA, Msx-2 and SM22α in VSMCs (n = 3). F. Representative bands of Western blotting of p-PERK, PERK, GRP78 and ATF4 in VSMCs (n = 3). One-way analysis of variance and Tukey’s post hoc test were used to compare multiple groups. *P < 0.05, **P < 0.01, ***P < 0.001 vs. Control.